Following one of Granddad's legendary soul food dinners, the Freeman family's friends happily pass out after the rich and fatty food causes them to be struck with what is called "The Itis." Listening to Granddad recount a dream about owning a restaurant filled with beds where diners could fall asleep after eating, banker and neighbor Ed Wuncler invites him to look at a health food restaurant he owns with an eye towards making a change. And after complaining about the politically liberal clientele that the Frutorium attracts, Ed fires nearly everyone on the staff before setting Granddad up in a restaurant they call the Itis Reeling in horror at Granddad's latest culinary creation, a half-pound bacon and cheese laden hamburger he calls "The Luther," the family's lone vegetarian, Huey, warns against going too far. Ignoring Huey's warnings, Granddad heads for the kitchen and, with Tom serenading the diners and Uncle Ruckus keeping the beds filled with customers, the Itis opens its doors. And even though Huey embarks on a campaign to convince the staff and diners that it's a health hazard, the food's addictive qualities make the Itis a big hit. Soon after opening, the restaurant's success begins to catch up with it. Because of their addiction to the food, the diners lose interest in everything except getting their next meal, turning what was once a prosperous upper class neighborhood into a crime-infested slum. In a matter of weeks, even Granddad begins to wonder if he may have made a mistake. And though Granddad continues to fight back against Huey's campaign, with the first wave of lawsuits filed against them, Ed pulls the plug and shuts the Itis down.