Prostate cancer (PCa) is the second most commonly diagnosed malignancy and a leading cause of cancer death in men across the globe. Current practices for detecting PCa utilize serum PSA and DRE as indications for biopsy and identify approximately 25% of patients with PCa. Unfortunately this means that 75% of biopsies are unnecessary, creating a considerable burden in terms of cost and patient discomfort. PCA3 is a prostate-specific gene that is highly overexpressed in prostate tumors ...