House takes on the case of 20-year-old female patient Tracy Dawson, who is rushed to Princeton Plainsboro Teaching Hospital with breathing difficulties and unexplained intense abdominal pain after she and her husband, Jeremy, are victims of a robbery. During Tracy's stress test, Jeremy collapses in the hospital viewing room, with test results leading the team to believe the couple's illnesses are related. Their strained relationship with Jeremy's father causes Tracy to hallucinate about a past incident when her father-in-law tried to hurt Jeremy for seeing her. The traumatic dream leaves Tracy in a coma and House wants to conduct a very risky biopsy on her brain stem, but Jeremy refuses to consent. House enlists Wilson's help to explain the potentially dangerous procedure and secure Jeremy's consent, but all does not go as planned; House discovers a new symptom that takes the case down a shocking new path and changes the course of the couples' lives forever. Meanwhile, House and clinic patient Michael Tritter (guest star David Morse) have a touchy altercation, leaving Tritter appalled and furious at the way House treated him.