The Organization for Security and Co-operation in Europe (OSCE) and Conference on Interaction and Confidence-Building Measures in Asia (CICA) have been playing a more active role on the world stage. Turkey assumed the Chairmanship of CICA in June 2010 and cooperated closely with Kazakhstan which had the Chairmanship of OSCE throughout 2010. Could the CICA and the OSCE, now headed by Lithuania, contribute even more to strengthening a regional approach in addressing regional problems?