Below is an info email from www.eatstopeat.com (Brad Pilon, author) ---------------------------------- Hi, As you can imagine, I receive lots of questions about Eat Stop Eat, with the most common question being about fasting and losing muscle. Most people are still very concerned that they will lose muscle if they don't eat every 3 hours. My answer has always been, don't worry, if you are resistance training then you won't lose muscle. The other day, I received a very interesting question that went something like this - "If calorie restriction doesn't cause muscle loss, then what does?" Great question. We all know that people who are bedridden and on a low calorie diet lose muscle. When I first starting writing Eat Stop Eat, and was running the idea past several dietitians for input, they all brought up stories of muscle loss in their patients who were bedridden and on a low calorie diet. And since I am constantly saying that caloric restriction doesn't cause you to lose muscle if you are working out, then that leaves being 'bedridden' (or 'disuse' as they say in research) as the cause of muscle loss. In my opinion, the best way to lose muscle it to not use muscle. Ever break your arm and have to wear a cast, or know someone who did? Do you remember how skinny that arm was when the cast finally came off? Put a cast on your arm and your muscles will shrink faster then an expensive new shirt in the dryer. There was no change in nutrition, only a change in the amount the muscles were used, and the muscle wasted away. In fact, 'casting' is so effective at causing muscle loss that it has been used in research to study something called 'disuse atrophy'or muscle loss from lack of use. In a study conducted at the University of Nottingham, 22 male and female studies had casts put on their right leg for two weeks. Their diets didn't change, yet after only two weeks the cross sectional area of their quadriceps (the big muscles in your thigh) decreased by 10%. NO change in diet..but the muscle still decreases in size by 10%. The Bottom line is as long as you are working out, and meeting some sort of caloric minimum (studies have gone as low as 80 grams of protein and 800 Kcals a day) you will not lose muscle. Most importantly you will definitely not lose muscle following Eat Stop Eat. However, since you will be losing weight, it means all the weight you lose will be fat. Brad www.EatStopEat.com