Doha's apparent failure has given rise to a debate on the role of multilateral, regional and bilateral factors in shaping the international trade agenda. Meanwhile, it remains unclear if, and how, businesses have been affected. • Akira Amari, Minister of Economy, Trade and Industry of Japan • Celso Amorim, Minister of Foreign Relations of Brazil • Pascal Lamy, Director-General, World Trade Organization (WTO), Geneva • Doris Leuthard, Federal Councillor of Economic Affairs of the Swiss Confederation • Peter Mandelson, Commissioner, Trade, European Commission, Brussels • Kamal Nath, Minister of Commerce and Industry of India • Susan Schwab, US Trade Representative Moderated by • John K. Defterios, Group Vice-President, Content and Anchor, United Kingdom, FBC Media, United Kingdom